Muslims like this question. Their point is this: If Jesus is God, how can God forsake God?
Along with this, there are other related questions:
Can your god die?
Who was running the universe while God was dead?
Death does not mean cessation of existence. Not for people like you and me, and even less for the Alpha and the Omega, Jesus.
This question gives you a great opportunity.
Jesus is actually quoting from the first words of Psalm 22. The psalms were not "numbered" at that time, but they would be commonly known by the first few words. The psalm describes a person crucified and finally vindicated. Jesus is saying that this psalm was fulfilled in their sight, just as in Luke 3, at the start of his ministry, he said that Isaiah's prophesy was fulfilled in their midst.
James White made a video on this topic:
Comments on Ally/Qureshi Debate
https://youtu.be/TsX6fhz-Bxs
Also this short video:
https://youtu.be/yecHbv06ZHI
